Peritonitis

Updated August 2026

Overview


Peritonitis is inflammation of the peritoneum, the lining of the abdominal cavity, most often caused by infection spreading from a ruptured organ such as the appendix or bowel. It is a surgical emergency requiring urgent treatment.

Symptoms of Peritonitis


  • Severe, widespread abdominal pain that worsens with movement or coughing
  • A rigid, board-like abdomen on examination
  • Fever
  • Nausea and vomiting
  • Signs of shock in advanced cases — rapid heart rate, low blood pressure

What Causes Peritonitis?


  • Most commonly results from rupture of an inflamed organ, such as a ruptured appendix, perforated peptic ulcer, or perforated bowel, spilling infected contents into the abdominal cavity.
  • Can also result from infection spreading from the female reproductive organs, or from complications of abdominal surgery.
  • Any condition causing a hole or leak in the gastrointestinal tract can lead to peritonitis if untreated.

How is Peritonitis Diagnosed?


  • Diagnosed clinically based on severe abdominal pain with a rigid abdomen and marked tenderness on examination.
  • Blood tests typically show signs of infection and inflammation.
  • Abdominal imaging, such as X-ray or ultrasound where available, can help identify the underlying cause, such as free air from a perforation.

Treatment for Peritonitis


Peritonitis is a surgical emergency requiring urgent hospital admission, intravenous fluids, and broad-spectrum intravenous antibiotics started as soon as the diagnosis is suspected.

Emergency surgery is usually needed to identify and repair the source of the infection, such as closing a perforation or removing a ruptured appendix, and to clean out infected material from the abdominal cavity.

Close monitoring for shock and organ dysfunction is essential, as peritonitis can progress rapidly to life-threatening sepsis.

Pain relief is given, but should not delay urgent surgical assessment.

How to Prevent Peritonitis


  • Seek prompt medical care for worsening or severe abdominal pain rather than waiting.
  • Seek timely treatment for conditions that can lead to peritonitis if untreated, such as appendicitis or peptic ulcer disease.
  • Follow medical advice closely after abdominal surgery, and report new or worsening abdominal pain promptly.
1 Source

Mfamasia's health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date health standards.

  1. Webpage Tanzania Standard Treatment Guidelines (STG) and National Essential Medicines List (NEMLIT), Ministry of Health, Community Development, Gender, Elderly and Children, United Republic of Tanzania, 2021 Edition..