Infertility

Medically reviewed by Joel Nyandigira Updated August 2026

Overview


Infertility is the inability to conceive after a year of regular, unprotected sexual intercourse (or six months for women over 35). It can result from factors affecting either partner, or a combination of both, and many cases can be successfully treated once the cause is identified.

Symptoms of Infertility


  • The primary symptom is difficulty conceiving despite regular, unprotected intercourse over an extended period
  • In women, irregular or absent menstrual periods can be a sign of an underlying cause affecting ovulation
  • In men, there are often no specific symptoms, and infertility may only become apparent through the inability to conceive

What Causes Infertility?


  • In women, common causes include irregular ovulation (such as with PCOS), tubal blockage (often related to past pelvic infection), and, less commonly, uterine abnormalities.
  • In men, common causes include low sperm count or quality, problems with sperm delivery, and hormonal imbalances.
  • In many couples, a combination of factors from both partners contributes, and in some cases, no specific cause is identified despite thorough evaluation.
  • Age, particularly for women, is an important factor, as fertility naturally declines with increasing age.

How is Infertility Diagnosed?


  • Evaluation typically involves both partners, since either or both may contribute to difficulty conceiving.
  • For women, assessment includes a menstrual and reproductive history, blood tests to assess ovulation and hormone levels, and, where available, imaging to assess the uterus and fallopian tubes.
  • For men, a semen analysis assesses sperm count, movement, and shape.
  • Further specialised testing may be considered depending on initial findings.

Treatment for Infertility


Treatment is guided by the identified cause where possible — for example, medicines to induce ovulation for women with irregular ovulation, or treatment of an underlying hormonal or structural problem.

Lifestyle factors such as maintaining a healthy weight, reducing alcohol intake, and stopping smoking can improve fertility for both partners and are generally recommended as a first step.

For couples where standard treatment does not lead to conception, or where the cause involves significant tubal or sperm factors, referral to a specialist fertility service for further options may be appropriate, where available.

Emotional support is an important part of care, as infertility can be a significant source of distress for couples.

How to Prevent Infertility


  • Maintain a healthy body weight and avoid excessive alcohol intake.
  • Avoid smoking, which can affect fertility in both men and women.
  • Seek prompt treatment for pelvic infections and sexually transmitted infections, which can affect future fertility if untreated.
  • Seek evaluation as a couple after a year of trying to conceive without success (or sooner for women over 35, or with known risk factors).
1 Source

Mfamasia's health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date health standards.

  1. Tanzania Standard Treatment Guidelines (STG) and National Essential Medicines List (NEMLIT), Ministry of Health, Community Development, Gender, Elderly and Children, United Republic of Tanzania, 2021 Edition.