Hand, Foot, and Mouth Disease

Medically reviewed by Joel Nyandigira Updated August 2026

Overview


Hand, foot, and mouth disease is a common, usually mild viral illness affecting mainly young children, causing sores in the mouth and a rash on the hands and feet. It typically resolves on its own within about a week.

Symptoms of Hand, Foot, and Mouth Disease


  • Fever
  • Painful sores or ulcers in the mouth, which can make eating and drinking uncomfortable
  • A rash of small blisters or spots on the hands, feet, and sometimes the buttocks
  • Reduced appetite and general irritability in young children
  • Sore throat

What Causes Hand, Foot, and Mouth Disease?


  • Caused by viruses, most commonly coxsackievirus, spread through close contact, respiratory droplets, or contact with fluid from blisters or contaminated surfaces.
  • Most common in children under five, though it can occur at any age.
  • Highly contagious, particularly in childcare and school settings.

How is Hand, Foot, and Mouth Disease Diagnosed?


  • Diagnosed clinically based on the characteristic pattern of mouth sores together with a rash on the hands and feet in a young child.

Treatment for Hand, Foot, and Mouth Disease


There is no specific antiviral treatment; management is supportive with adequate fluids, paracetamol or ibuprofen for fever and discomfort, and soft, cool foods that are easier to eat with mouth sores.

Most children recover fully within about a week without complications.

Ensuring adequate fluid intake is particularly important, as painful mouth sores can lead some children to refuse drinking, increasing the risk of dehydration.

Medical assessment is recommended if a child shows signs of dehydration, has a high or persistent fever, or seems unusually unwell.

How to Prevent Hand, Foot, and Mouth Disease


  • Practise good hand hygiene, particularly after nappy changes and before eating.
  • Avoid close contact with an infected child, and clean shared toys and surfaces regularly.
  • Keep children with active symptoms away from childcare or school until they are feeling better and any fever has resolved, per local facility guidance.
  • Encourage frequent, small amounts of fluid, even if the child is reluctant due to mouth soreness.
1 Source

Mfamasia's health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date health standards.

  1. World Health Organization (WHO); Centers for Disease Control and Prevention (CDC); Mayo Clinic; Cleveland Clinic — general clinical reference sources.