Corneal Ulcer (Keratitis)

Medically reviewed by Joel Nyandigira Updated August 2026

Overview


A corneal ulcer is an open sore on the cornea, the clear front surface of the eye, most often caused by infection. It is a serious eye condition that can threaten vision if not treated promptly.

Symptoms of Corneal Ulcer (Keratitis)


  • Eye pain, often significant
  • Redness of the eye
  • Sensitivity to light (photophobia)
  • Blurred vision
  • Discharge from the eye
  • A visible white or grey spot on the cornea may be seen with careful examination

What Causes Corneal Ulcer (Keratitis)?


  • Most commonly caused by bacterial, viral, or fungal infection of the cornea.
  • Risk is significantly increased by contact lens wear, particularly with poor hygiene or overnight wear, and by prior eye injury or trauma, especially involving plant material for fungal infection.
  • Dry eye and other conditions affecting the eye's surface can also increase susceptibility.

How is Corneal Ulcer (Keratitis) Diagnosed?


  • Diagnosed through eye examination, ideally with magnification, looking for the characteristic ulcer and associated inflammation.
  • A sample of the ulcer material may be taken for laboratory testing, where available, to identify the specific causative organism, particularly for more severe or non-improving cases.
  • Contact lens wearers or anyone with a red, painful eye and reduced vision should be assessed urgently.

Treatment for Corneal Ulcer (Keratitis)


A corneal ulcer is an eye emergency requiring urgent referral to a facility with eye care capability, as delayed treatment risks permanent scarring and vision loss.

Treatment depends on the underlying cause — intensive antibiotic eye drops for bacterial infection, antiviral treatment for viral causes, or antifungal treatment for fungal infection — often started frequently, sometimes hourly initially for bacterial ulcers.

Contact lens wear should be stopped immediately if a corneal ulcer is suspected.

Close follow-up is needed to monitor healing and adjust treatment, as corneal ulcers can worsen quickly and some causes require prolonged treatment courses.

How to Prevent Corneal Ulcer (Keratitis)


  • Practise strict contact lens hygiene, including proper cleaning, storage, and avoiding overnight wear unless specifically approved for that use.
  • Never wear contact lenses while swimming or in water without appropriate protection.
  • Seek prompt eye protection when working with plant material, soil, or in environments with risk of eye injury.
  • Seek urgent medical assessment for any painful, red eye with reduced vision or light sensitivity, rather than treating it as a minor irritation.
1 Source

Mfamasia's health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date health standards.

  1. Tanzania Standard Treatment Guidelines (STG) and National Essential Medicines List (NEMLIT), Ministry of Health, Community Development, Gender, Elderly and Children, United Republic of Tanzania, 2021 Edition.