Corneal Ulcer (Keratitis)

Updated August 2026

Overview


A corneal ulcer is an open sore on the cornea, the clear front surface of the eye, most often caused by infection. It is a serious eye condition that can threaten vision if not treated promptly.

Symptoms of Corneal Ulcer (Keratitis)


  • Eye pain, often significant
  • Redness of the eye
  • Sensitivity to light (photophobia)
  • Blurred vision
  • Discharge from the eye
  • A visible white or grey spot on the cornea may be seen with careful examination

What Causes Corneal Ulcer (Keratitis)?


  • Most commonly caused by bacterial, viral, or fungal infection of the cornea.
  • Risk is significantly increased by contact lens wear, particularly with poor hygiene or overnight wear, and by prior eye injury or trauma, especially involving plant material for fungal infection.
  • Dry eye and other conditions affecting the eye's surface can also increase susceptibility.

How is Corneal Ulcer (Keratitis) Diagnosed?


  • Diagnosed through eye examination, ideally with magnification, looking for the characteristic ulcer and associated inflammation.
  • A sample of the ulcer material may be taken for laboratory testing, where available, to identify the specific causative organism, particularly for more severe or non-improving cases.
  • Contact lens wearers or anyone with a red, painful eye and reduced vision should be assessed urgently.

Treatment for Corneal Ulcer (Keratitis)


A corneal ulcer is an eye emergency requiring urgent referral to a facility with eye care capability, as delayed treatment risks permanent scarring and vision loss.

Treatment depends on the underlying cause — intensive antibiotic eye drops for bacterial infection, antiviral treatment for viral causes, or antifungal treatment for fungal infection — often started frequently, sometimes hourly initially for bacterial ulcers.

Contact lens wear should be stopped immediately if a corneal ulcer is suspected.

Close follow-up is needed to monitor healing and adjust treatment, as corneal ulcers can worsen quickly and some causes require prolonged treatment courses.

How to Prevent Corneal Ulcer (Keratitis)


  • Practise strict contact lens hygiene, including proper cleaning, storage, and avoiding overnight wear unless specifically approved for that use.
  • Never wear contact lenses while swimming or in water without appropriate protection.
  • Seek prompt eye protection when working with plant material, soil, or in environments with risk of eye injury.
  • Seek urgent medical assessment for any painful, red eye with reduced vision or light sensitivity, rather than treating it as a minor irritation.
1 Source

Mfamasia's health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date health standards.

  1. Webpage Tanzania Standard Treatment Guidelines (STG) and National Essential Medicines List (NEMLIT), Ministry of Health, Community Development, Gender, Elderly and Children, United Republic of Tanzania, 2021 Edition..